New study from obesity scientist Stephan Guyenet showing that leptin resistance in the brain (the primary defect associated with obesity) can be reversed in rodents WITHOUT forced calorie restriction by making one simple change: Following a diet of unrefined food.
First step is put the rodents on a high fat diet so they become leptin resistant and obese.
Once they are obese, switch them to a 100% unrefined food diet and simply let them eat as much unrefined food as they want.
Guess what happens?
The obesity and leptin resistance are REVERSED, and the rodents become lean.
Like I say in my book, the single greatest predictor of leanness is the extent to which you eat a diet of whole, unrefined, single-ingredient foods that you prepare at home.